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Control products and reagents designed for clinical testing procedures. Ideal for use in performing, calibrating, monitoring, and ensuring the accuracy of diagnostic tests such as immunoassays.
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DSPE-PEG2000-GE11 is a nanocarrier component composed of DSPE and the EGFR-targeting peptide (GE11). It specifically binds to EGFR, mediating receptor-mediated endocytosis of micellar drug carriers for drug delivery.
Specifically binds to EGFR.
Mediates receptor-mediated endocytosis of micellar drug carriers.
Enhances EGFR-dependent cellular uptake of doxorubicin (1.4-fold higher in SMMC-7721 cells).
Inhibits HUVEC proliferation, induces G2-M phase arrest, reduces cell migration, and alters HUVEC morphology when modified.
Enhances tumor accumulation of DiR-loaded micelles in EGFR-positive hepatocellular carcinoma xenografts.
Confers EGFR-targeted accumulation to liposomal formulations in liver cancer xenografts.
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DSPE-PEG2000-PDP is a phospholipid PEG conjugate utilized in drug delivery applications. It has a molecular weight of 2000 (average) and a CAS number of 474922-24-2. The product appears as a solid with a white to off-white color. It boasts a purity of 90.0%.
Molecular weight of 2000 (average)
Solid appearance with a white to off-white color
Purity of 90.0%
Utilized in drug delivery applications
Functions as a phospholipid PEG conjugate
Can act as an inhibitor
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C18:1 Glucosyl(ß) Ceramide (d18:1/18:1(9Z)) is a high-purity glycosphingolipid from Avanti Polar Lipids. This ceramide consists of an oleoyl fatty acid chain and a D-erythro-sphingosine base, and is available in a 5 mg quantity. The empirical formula is C42H79NO8, with a molecular weight of 726.079, making it valuable for lipid biology research.
High-purity glycosphingolipid
Available in 5 mg quantity
Empirical formula: C42H79NO8
Molecular weight: 726.079
Lipid class: Glycosphingolipid, Ceramide
Fatty acid: 9Z-octadecenoyl (Oleoyl)
Sphingoid base: D-erythro-sphingosine (d18:1)
Physical form: Powder
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1-Palmitoyl-sn-glycero-3-phosphocholine-d49 is the deuterium-labeled isotopologue of 1-palmitoyl-sn-glycero-3-phosphocholine (16:0 Lyso PC). Supplied as a solid, it is used as an analytical reference and internal standard in lipidomics and mass spectrometry workflows to enable accurate quantitation of lysophosphatidylcholine species.
Isotopically labeled with 49 deuterium atoms (d49).
Chemical formula C24HD49NO7P.
Molecular weight 544.93.
CAS number 2315262-40-7.
Supplied as a solid in small pack sizes, suitable for analytical use.
Intended for use as an internal standard in LC-MS/MS and lipid analysis.
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An ionizable cationic lipid; has been used in the formation of LNPs; LNPs containing DLin-MC2-DMA and encapsulating siRNA targeting mRNA encoding FVII reduce hepatic levels of FVII in mice (ED50 = 0.6 mg/kg)
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DSPE-PEG (2000)-COOH is a pegylated derivative of 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine. This compound can form micelles, making it suitable for targeted drug delivery applications. It is intended for research use only.
Forms micelles for targeted drug delivery.
High purity: 99.95%.
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A triacylglycerol; has been found in Kpangnana, Chinese tallow, and cocoa butters; increases the phagocytic function of reticulo-endothelial cells in mice at 5 and 10 mg per animal
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